![]() In addition, questions remain how to raise motivation. However, awareness in the general population about the relationship between lifestyle and dementia risk is low and raising awareness is crucial for the required behavioral change. To optimize this potential of primary prevention of dementia, applying the existing knowledge to prevention strategies is essential. Most of these risk factors were also incorporated in the dementia risk reduction guidelines of the World Health Organization. This is underscored by the 2020 report of the Lancet Commission on Dementia Prevention, Intervention, and Care that concluded that a total of 12 modifiable factors account for around 40% of the people with dementia worldwide. ![]() There is increasing evidence that dementia is associated with modifiable risk and protective factors, such as smoking, obesity, and physical inactivity, which opens up the opportunity for primary prevention.
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